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006 m o d |
007 cr cn|||||||||
008 120119s2012 enka sb 001 0 eng d
010 _z 2012002555
020 _z9781405185745
020 _a9781118345337 (electronic bk.)
035 _a(MiAaPQ)EBC938872
035 _a(Au-PeEL)EBL938872
035 _a(CaPaEBR)ebr10580247
035 _a(CaONFJC)MIL367513
035 _a(OCoLC)795120561
040 _aMiAaPQ
_cMiAaPQ
_dMiAaPQ
050 4 _aQR189
_b.V33 2012
082 0 4 _a615.3/72
_223
245 0 0 _aVaccinology
_h[electronic resource] :
_bprinciples and practice /
_cedited by W. John W. Morrow ... [et al.].
260 _aChichester [England] :
_bWiley-Blackwell,
_c2012.
300 _axii, 540 p. :
_bill.
504 _aIncludes bibliographical references and index.
505 8 _aMachine generated contents note: List of ContributorsPrefacePart 1: Introduction1 Concept & Scope of Modern VaccinesNadeem Sheikh PhD, Huw Davies PhD, Clint Schmidt PhDPart 2: Principles of Vaccine Design2 Strategies to Stimulate Innate Immunity for Designing Effective Vaccine AdjuvantsHeather L. Wilson PhD, Scott Napper PhD, George K. Mutwiri, Sylvia van Drunen-Little van den Hurk, Hugh Townsend PhD VIDO, Lorne A. Babiuk PhD, Andrew A. Potter PhD, Volker Gerdts PhD3 Antigen Processing and Presentation by MHC Class I, II and Non-Classical MoleculesAnthony N. Antoniou PhD, Izabela Lenart, David B. Guiliano, Simon J. Powis PhD4 Understanding the Mucosal Immune System for Better Mucosal VaccineJanine Bilsborough PhD, Joanne L. Viney PhD5 Immunological Memory: T Cells in HumansMaria Candela Iglesias, Victor Appay PhD, Arnaud Moris,6 Immunological Memory: B CellsFrances Eun-Hyung Lee MD, Inaki Sanz MD7 Utility of Mouse Models in Vaccine Design and DevelopmentCatherine M. Bosio PhD, Megan McLeod PhD, Philippa Marrack PhD, Ross M. Kedl8 Utility of Non-Human Primate Models for VaccinePreston A. Marx PhD, Alexander F. VoevodinPart 3: Antigen Discovery (Macro approach vs. Epitope focused)9 Sequence Based Computational Approaches to Vaccine Discovery and DesignDarrick Carter PhD10 High-Throughput Proteomics (Microarrays only)Huw Davies PhD11 Phage LibrariesAaron K. Sato PhDPart 4: Antigen Engineering12 Attenuated Microbial VaccinesRichard W. Titball BSc, FRCPath, Helen S. Atkins BSc, PhD13 Virus-Like Particles as Antigen ScaffoldsBryce Chackerian PhD, John T. Schiller PhD14 Recombinant MVA Vaccines, Optimisation, Pre-clinical and Product DevelopmentYper Hall BSc, Miles Carroll PhD15 Recombinant Adenoviruses for VaccinationNelson Cesar Di Paolo PhD, Dmitry Shayakhmetov PhD, Andre; Lieber MD, PhD16 Recombinant AvipoxvirusesMichael A. Skinner PhD, Stephen M. Laidlaw17 Intracellular Facultative Bacterial Vectors For Cancer ImmunotherapyPatrick Guirnalda , Laurence Wood, Matthew Seavy, Yvonne Paterson PhD18 Nucleic Acid VaccinationBritta Wahren, Margaret A. Liu MD19 Artificial Antigen-presenting Cells: Large Multivalent ImmunogensMatthew F. Mescher PhD, Julie M. CurtsingerPart 5: Delivery Systems20 Transcutaneous Immunization via Vaccine Patch Delivery SystemRobert C. Seid PhD, Gregory M. Glenn MD21 Needle-free Jet Injection for Vaccine AdministrationBrian R. Sloat, Hoi K. Tran, Zhengrong Cui PhD22 Oral Vaccines: an old need and some new possibilitiesAmit A. Lugade PhD, Kalathil Suresh PhD, Yasmin Thanavala PhD23 Adjuvants: From Serendipity to Rational DiscoveryDerek T. O'Hagan PhD, Andreas Wack PhD24 Immunostimulatory Properties of Biodegradable MicroparticlesF.A. Sharp, E.C. Lavelle25 Co-administration of Costimulatory MoietiesCarolina Arancibia, Yvette Latchman PhD26 Toll Receptors in Relation to Adjuvant EffectsDipshikha Chakravortty PhD, Amit Lahiri PhD, Priyanka Das PhDPart 6: Regulatory Considerations27 Regulatory Issues (FDA & EMEA)Murrium Ahmad PhD, Victoria Byers, Peter WilsonPart 7: Evaluating Vaccine Efficacy28 Immune Monitoring Design within the Development Pipeline for an Immunotherapeutic or Preventive VaccineSylvia Janetzki PhD, Pedro Romero MD, Mario Roederer PhD, Diane L. Bolton PhD, Camilla Jandus29 Clinical Development Strategy: Nuts and BoltsCandida Fratazzi MD, Claudio Carini MD, PhD30 Current Approaches to Identify and Evaluate Cancer Biomarkers for Patient StratificationRobert C Rees PhD, Stephanie Laversin, Cliff Murray PhD, Graham Ball PhDPart 8: Implementing Immunizations/Therapies31 Mass Immunization StrategiesDavid L. Heymann MD, DTM&H, Bruce R. Aylward, Rudolf H. Tangermann32 The Role of Mathematical Models in Vaccine Development and Public Health Decision MakingMarie-Claude Boily PhD, Marc Brisson PhD, Benoit Masse PhD, Sir Roy M Anderson FRS, FMedSci33 Vaccine SafetyJohn Iskander MD, MPH, Claudia Vellozzi MD, MPH, Jane Gidudu MD, MPH, Robert T. Chen MD, MA.
520 _a"This book addresses a profound deficiency in the field of vaccine research and development, namely the lack of a single volume describing the design and construction of vaccine strategies from first principles to implementation. This is an authoritative textbook that details a comprehensive and systematic approach to the science of vaccinology focusing on not only basic science, but the many stages required to commercialize and navigate the regulatory requirements for human application both in the United States and Europe. The book has broad appeal to clinicians, scientific and medical researchers alike, and graduate students"--Provided by publisher.
533 _aElectronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
650 0 _aVaccines.
650 0 _aVaccination.
655 4 _aElectronic books.
700 1 _aMorrow, John,
_d1949-
710 2 _aProQuest (Firm)
856 4 0 _uhttps://ebookcentral.proquest.com/lib/bacm-ebooks/detail.action?docID=938872
_zClick to View
999 _c79823
_d79823