000			04326nam a22005293i 4500
001			EBC5452806
003			MiAaPQ
005			20240122001111.0
006			m o d |
007			cr cnu||||||||
008			231124s2018 xx o ||||0 eng d
020			_a9783319946108 _q(electronic bk.)
020			_z9783319946092
035			_a(MiAaPQ)EBC5452806
035			_a(Au-PeEL)EBL5452806
035			_a(OCoLC)1048662300
040			_aMiAaPQ _beng _erda _epn _cMiAaPQ _dMiAaPQ
050		4	_aR723-723.7
100	1		_aParkkinen, Veli-Pekka.
245	1	0	_aEvaluating Evidence of Mechanisms in Medicine : _bPrinciples and Procedures.
250			_a1st ed.
264		1	_aCham : _bSpringer International Publishing AG, _c2018.
264		4	_c�2018.
300			_a1 online resource (131 pages)
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
490	1		_aSpringerBriefs in Philosophy Series
505	0		_aIntro -- Foreword -- Preface -- References -- Acknowledgements -- Contents -- Abstract -- Part I Why Consider Mechanisms? -- 1 Introduction -- 1.1 What is the Key Evidence? -- 1.2 The Process of Evaluating Evidence -- 1.3 Our Approach to Evaluating Evidence -- References -- 2 An Introduction to Mechanisms -- 2.1 Mechanisms at a Glance -- 2.2 What is a Mechanism? -- 2.3 Why Consider Evidence of Mechanisms? -- References -- 3 How to Consider Evidence of Mechanisms: An Overview -- 3.1 Questions to Address -- 3.2 Quality of Evidence and Status of Claim -- 3.3 Overall Approach -- References -- Part II Tools for Working with Mechanisms -- 4 Tools -- 4.1 Introduction -- 4.2 Is Your Policy Really Evidence-Based? -- 4.3 Mechanisms in Clinical Research Appraisal Tool -- 4.4 Mechanisms in Basic Science Research Appraisal Tool -- 4.5 Critical Appraisal Tool for Evidence of Mechanisms -- 4.6 GRADE-Style Tables for Mechanism Assessment -- 4.7 Public Health and Social Care Tool -- References -- Part III Core Principles -- 5 Gathering Evidence of Mechanisms -- 5.1 Identify Specific Mechanism Hypotheses -- 5.2 Formulate the Review Questions -- 5.3 Search the Literature -- 5.4 Refine Results of the Search -- 5.5 Presenting the Evidence of Mechanisms -- 5.6 Worked Example on Probiotics and Dental Caries -- References -- 6 Evaluating Evidence of Mechanisms -- 6.1 Overview -- 6.2 Evaluating Mechanistic Studies -- 6.3 Determining the Status of the General Mechanistic Claim -- 6.4 Presenting the Quality of Evidence of Mechanisms -- References -- 7 Using Evidence of Mechanisms to Evaluate Efficacy and External Validity -- 7.1 Efficacy -- 7.2 External Validity -- 7.3 Presenting the Status of a Causal Claim -- References -- Part IV Particular Applications -- 8 Assessing Exposures -- 8.1 Comparison to IARC -- 8.2 Comparison to SYRINA -- References.
505	8		_a9 Assessing Mechanisms in Public Health -- 9.1 Introduction -- 9.2 Public Health and Evidence-Based Medicine in the UK -- 9.3 Statistical Associations and Correlations in Public Health -- 9.4 Recurrent Public Health Problems -Non-communicable Disease in the Present -- 9.5 The Individual Level and the Population Level -- 9.6 The Biological Level and the Social Level -- 9.7 Mechanisms of Disease and Mechanisms of Prevention -- References -- 10 Particularisation to an Individual -- References.
588			_aDescription based on publisher supplied metadata and other sources.
590			_aElectronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
655		4	_aElectronic books.
700	1		_aWallmann, Christian.
700	1		_aWilde, Michael.
700	1		_aClarke, Brendan.
700	1		_aIllari, Phyllis.
700	1		_aKelly, Michael P.
700	1		_aNorell, Charles.
700	1		_aRusso, Federica.
700	1		_aShaw, Beth.
700	1		_aWilliamson, Jon.
776	0	8	_iPrint version: _aParkkinen, Veli-Pekka _tEvaluating Evidence of Mechanisms in Medicine _dCham : Springer International Publishing AG,c2018 _z9783319946092
797	2		_aProQuest (Firm)
830		0	_aSpringerBriefs in Philosophy Series
856	4	0	_uhttps://ebookcentral.proquest.com/lib/bacm-ebooks/detail.action?docID=5452806 _zClick to View
999			_c304589 _d304589