Peters, Sheila Annie. <br/><br/>
Physiologically-based pharmacokinetic (PBPK) modeling and simulations  principles, methods, and applications in the pharmaceutical industry /  [electronic resource] : 
Sheila Annie Peters. 
 - Hoboken, N.J. :  Wiley,  c2011. 
 - xvii, 430 p. :  ill. 
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain. 
<br/><br/><br/>Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. 
<br/><br/><label>ISBN: </label>9781118140383 (electronic bk.) 
<br/><br/><label>LCCN: </label>
<br/><br/><label>Subjects--Topical Terms: </label><br/>Pharmacokinetics--Mathematical models.<br/>Drugs--Design--Mathematical models.
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>RM301.5  / .P48 2011 
<br/><br/><label>Dewey Class. No.: </label>615/.7