TY  - BOOK
AU  - Patlak,Margie
AU  - Nass,Sharyl J.
ED  - National Cancer Policy Forum (U.S.)
ED  - Institute of Medicine (U.S.)
ED  - ProQuest (Firm)
TI  - Improving the quality of cancer clinical trials: workshop summary 
AV  - RC270.8 .I47 2008
U1  - 362.196/994007 22
PY  - 2008///
CY  - Washington, D.C.
PB  - National Academies Press
KW  - Cancer
KW  - Treatment
KW  - United States
KW  - Clinical trials
KW  - Electronic books
N1  - Includes bibliographical references; Introduction -- New clinical trial designs. Phase 0 trials -- Adaptive trial designs -- Targeting multiple pathways with multiple drugs -- Preclinical model systems -- Molecular imaging. Current and developing methods -- Challenges of molecular imaging -- Screening for predictive markers. The challenges of clinical validation -- Bioimaging predictive markers -- Clinical translation -- Panel discussion -- Costs of clinical trials. Regulatory costs -- Patient accrual -- Global outsourcing -- Time is money -- Public-private collaborations -- Regulatory issues. Regulatory barriers to innovation -- Patient advocacy perspective -- Regulation of in vitro diagnostics -- Regulatory issues in improving cancer clinical trials -- Reports from the case study discussion groups. Adaptive trial design -- Phase 0 trials -- Imaging -- Use of proteomics/genomics to assign therapy in lung cancer -- Use of genetics/genomics to assign therapy; Also available on the World Wide Web; Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries
UR  - https://ebookcentral.proquest.com/lib/bacm-ebooks/detail.action?docID=3378368
ER  -