Plasmid biopharmaceuticals [electronic resource] : basics, applications, and manufacturing / Duarte Miguel F. Prazeres.
Material type: TextPublication details: Hoboken, N.J. : John Wiley & Sons, c2011Description: xix, 590 p. : illISBN: 9780470939871 (electronic bk.); 9781118002254 (electronic bk.); 9780470939871 (electronic bk.)Subject(s): Plasmids | BiopharmaceuticsGenre/Form: Electronic books.DDC classification: 615/.1 LOC classification: QH452.6 | .P73 2011Online resources: Click to ViewIncludes bibliographical references and index.
Historical perspective -- Gene transfer with plasmid biopharmaceuticals -- Product and process development -- Structure -- Analytical characterization -- Delivery -- Ethical and safety issues -- Human and veterinary markets -- Human case studies : pandemic influenza and critical limb ischaemia -- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma -- GMPS and validation -- Product specifications and quality control -- Cell culture -- An overview of downstream processing -- Primary isolation -- Intermediate recovery -- Final purification -- Process synthesis -- Concluding remarks and outlook.
Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.
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