Gene Drives at Tipping Points : (Record no. 305706)
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| 000 -LEADER | |
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| fixed length control field | 09871nam a22004333i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC6191312 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240122001212.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231124s2020 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9783030389345 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9783030389338 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC6191312 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL6191312 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)1152535309 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | TD193-193.5 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | von Gleich, Arnim. |
| 245 10 - TITLE STATEMENT | |
| Title | Gene Drives at Tipping Points : |
| Remainder of title | Precautionary Technology Assessment and Governance of New Approaches to Genetically Modify Animal and Plant Populations. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Cham : |
| Name of producer, publisher, distributor, manufacturer | Springer International Publishing AG, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2020. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | �2020. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (264 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Intro -- Acknowledgements -- Introduction -- Contents -- Contributors -- Abbreviations -- Species List -- 1 Technology Characterisation -- Introduction -- SPAGE-Techniques -- Gene Drives -- Methodology of Technology Characterisation -- Depth of Intervention (Technological Power and Range) -- Intensity of Intervention (Number/Frequency) -- Reliability of the Technology -- Corrigibility or Limitation of Damage in Case of Failure -- Important Preliminary Remarks -- SPAGE Technologies -- Release of Insects Carrying a Dominant Lethal Gene (RIDL) -- Meiotic Drives (MD) in particular X-Shredder -- Killer-Rescue -- Maternal-Effect Dominant Embryonic Arrest (Medea) -- Underdominance (UD) -- Homing Endonuclease Genes (HEG) -- CRISPR/Cas9 -- Summary of the Technology Characterisation -- References -- 2 Gene Drives Touching Tipping Points -- The Relevance of Tipping Points to Understand Implications of Deliberate Release of Self Propagating Artificial Genetic Elements (SPAGE) -- Conceptual Background: Phase Transitions in Dynamic Systems -- Examples in Different Scientific Domains -- Concepts and Applications in Dynamic Theory: Important Forms of Phase Transitions Where Tipping Points Mark Domain Boundaries -- Potential Tipping Points with SPAGE Involvement -- A Hierarchy in Consideration Levels: Where SPAGE-Related Tipping Points Could Occur -- Tipping Points on the Molecular and Physiological Level -- Tipping Points on the Population Level -- Tipping Points on the Ecosystem Level -- Tipping Points on the Landscape and (Cross-) Regional Level -- Tipping Points in an Evolutionary Context -- Tipping Point Considerations with Regard to a Social Ecological Domain of SPAGE-The Interaction of Natural and Social Processes -- Tipping Points in Application and Feasibility Considerations -- Tipping Points in Risk Assessment and Management. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Tipping Points in Regulation and Law Enforcement -- Tipping Points in Social Acceptance -- Discourse Outlook -- References -- 3 Vulnerability Analysis of Ecological Systems -- Introduction -- Ecosystem Vulnerability Analysis -- Exposure -- Sensitivity -- Adaptive Capacity -- Event-Based Analysis of Vulnerability -- Potential Tipping Events Caused by GDO -- Structural Analysis of Vulnerability -- Resilience of Ecosystems -- Regime Shifts and Resilience -- Summary -- References -- 4 Case Study 1: Olive Fruit Fly (Bactrocera oleae) -- Population Biology -- Phenology -- Population Characteristics -- Environmental Tolerances -- Dispersal Dynamics -- Dispersal Distances -- Genetic Variability and Gene Flow -- Potential Hazards with Regard to Gene Drive Release -- Unintentional Long-Distance Transport of the Genetically Modified Organism -- Hybridization and Horizontal Gene Transfer Across Species Boundaries -- Ecological Niche Filling by Other Species -- Concluding Remark -- References -- 5 Case Study 2: Oilseed Rape (Brassica napus L.) -- Intention and Scope of the Case Study Oilseed Rape (Brassica napus) -- Oilseed Rape-Biological and Ecological Characteristics -- Production, Uses and Genetic Modification -- Potential Hybridisation Partners -- Conclusions on Gene Flow Potential -- Pests and Pathogens -- Pollen Transfer and Gene Flow -- Gene Flow by Airborne Pollen Transport -- Lineage-Specific Factors of Actual Gene Flow -- Not-Lineage-Specific Factors of Actual Gene Flow -- Gene Flow via Pollen Transport by Insects -- Seed Persistence and Germination in Oilseed Rape -- Genetic Modifications in Oilseed Rape -- Persistence of Genetically Modified Oilseed Rape Outside Fields -- General Implications -- Agricultural Implications -- Conservation Implications -- Detection of Unintended Spread of Transgenic Oilseed Rape in Various Countries. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Modelling Approaches for Gene Drives -- GeneSys -- GeneTraMP -- Model Suitability to Represent Gene Drive Population Dynamics -- Suitability and Prerequisites of Oilseed Rape for Gene Drives? -- Purposes for Oilseed Rape Gene Drives? -- Gene Drives to Delete/Block Herbicide Resistances -- CRISPR/Cas-Based Approaches -- Resistance Blocking -- Overwriting Various Herbicide Resistances with a Single Resistance -- Self-Limiting CRISPR/Cas-Based Approaches -- Gene Drive Seeds as a Breeding Tool on Agricultural Fields -- Female Infertility Drive -- Other Gene Drive Techniques Besides CRISPR/Cas -- Conclusion -- References -- 6 Model Concepts for Gene Drive Dynamics -- Introduction -- Stock-Flow Model of an Olive Fly Population -- Stock-Flow Model of a Single-Locus Underdominance Gene Drive -- Stock-Flow Model of a Medea Gene Drive -- Deterministic Recurrence-Based Calculations on the Inheritance Schemes of Different Gene Drive Techniques -- Stochastic Model Considering an Olive Fly Population with Gene Drive and Bottlenecks -- Differential Equation-Based Modelling of an Olive Fly Population with a Gene Drive -- Individual-Based Model of an Olive Fly Population with Gene Drive -- Conclusion -- References -- 7 Alternative Techniques and Options for Risk Reduction of Gene Drives -- Introduction -- Intrinsic Containment -- Safety Options for GDO-Releases -- Molecular Modifications of Gene Drives as Safety Strategy -- Limitation by Secondary Releases -- Limitation by Dependence -- Limitation by Genetic Instability -- Alternative Approaches to Synthetic Gene Drives -- Overview of Potential Safety Mechanisms -- Summary -- References -- 8 Limits of Knowledge and Tipping Points in the Risk Assessment of Gene Drive Organisms -- Introduction -- The Production of Knowledge and Non-knowledge -- The Science of Non-knowledge in Upstream Technology Assessment. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | The Exploration of Non-knowledge in the Field of Biotechnology -- Some 'Known Unknowns' in Regard to Risk Assessment of GE Organisms and New Challenges Posed by Gene Drives -- Conceptual Challenges in Risk Assessment of GE Organisms -- Specific Characteristics of GE Organisms -- Specific Challenges in Risk Assessment of Gene Drives -- Some Reasons for Concern Arising from Existing Evidence -- The EFSA Concept and the Problem of Spatio-Temporal Complexity -- The Current EFSA System and Its Approach to Future Applications -- Some Relevant Aspects of Spatio-Temporal Complexity -- Problems Emerging from Spatio-Temporal Complexity for Risk Assessment -- 'Spatio-Temporal Controllability' as a Cut-Off Criterion -- Lessons Learned from Risk Assessment of Chemicals -- Cut-Off Criteria in the Risk Assessment of GE Organisms -- Case Studies: How to Apply 'Spatio-Temporal Controllability' in Practice -- The Role of the Risk Manager -- Discussion -- Conclusions -- References -- 9 Steps Towards a Precautionary Risk Governance of SPAGE Technologies Including Gene-Drives -- Reasons for Concern as an Interface Between Risk Assessment and Risk Management -- Dealing with Non-knowledge: Precautionary, Prospective Technology Assessment Versus Environmental Risk Assessment -- Depth of Intervention -- Identification of Substances of Very High Concern in REACH -- Operationalization of the Precautionary Principle in the Governance of GMOs Along the Lines of REACH -- Conclusion -- Five Steps Towards Integrating the Precautionary Principle into the Governance of SPAGE -- References -- Summary -- References -- Index. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2023. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schr�oder, Winfried. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | von Gleich, Arnim |
| Title | Gene Drives at Tipping Points |
| Place, publisher, and date of publication | Cham : Springer International Publishing AG,c2020 |
| International Standard Book Number | 9783030389338 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/bacm-ebooks/detail.action?docID=6191312">https://ebookcentral.proquest.com/lib/bacm-ebooks/detail.action?docID=6191312</a> |
| Public note | Click to View |
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